The prevalence and risk factors of allergic rhinitis from a nationwide study of Korean elementary, middle, and high school students.
10.4168/aard.2015.3.4.272
- Author:
Yeongho KIM
1
;
Ju Hee SEO
;
Ji Won KWON
;
Eun LEE
;
Song I YANG
;
Hyun Ju CHO
;
Mina HA
;
Eunae BURM
;
Kee Jae LEE
;
Hwan Cheol KIM
;
Sinye LIM
;
Hee Tae KANG
;
Mia SON
;
Soo Young KIM
;
Hae Kwan CHEONG
;
Yu Mi KIM
;
Gyung Jae OH
;
Joon SAKONG
;
Chul Gab LEE
;
Sue Jin KIM
;
Yong Wook BEAK
;
Soo Jong HONG
Author Information
1. Department of Pediatrics, Childhood Asthma Atopy Center, Environmental Health Center, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. sjhong@amc.seoul.kr
- Publication Type:Original Article
- Keywords:
Allergic rhinitis;
Prevalence;
Risk factors;
Sensitization;
Child
- MeSH:
Adolescent;
Allergens;
Alnus;
Ambrosia;
Animals;
Artemisia;
Asian Continental Ancestry Group;
Asthma;
Betula;
Cats;
Child;
Dermatophagoides pteronyssinus;
Dogs;
Female;
Fungi;
Humans;
Humulus;
Hypersensitivity;
Korea;
Male;
Odds Ratio;
Parents;
Prevalence*;
Pyroglyphidae;
Rhinitis*;
Risk Factors*;
Skin
- From:Allergy, Asthma & Respiratory Disease
2015;3(4):272-280
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: We investigated the prevalence and risk factors of allergic rhinitis (AR), nationwide in random children and adolescents of Korea. METHODS: A modified International Study of Asthma and Allergies in Childhood (ISAAC) questionnaire survey was done in 1,820 children from elementary, middle, and high school nationwide in Korea. The subjects were selected by the stratifying sampling method by school grade and five regions. Current AR was defined as having AR symptoms during the last 12 months with a history of physician-diagnosed AR. Skin prick tests for 18 common allergens were performed. RESULTS: The number of males was 945, and that of females was 875. The mean age of the patients was 12.61+/-3.40 years. The prevalence of current AR and atopic current AR were 29.0% and 18.7%, respectively. Risk factors for current AR were male (adjusted odds ratio [aOR], 1.486; 95% confidence interval [CI], 1.189-1.856), family history of paternal AR (aOR, 3.208; 95% CI, 2.460-4.182), family history of maternal AR (aOR, 3.138; 95% CI, 2.446-4.025), antibiotic use in infancy (aOR, 1.547; 95% CI, 1.228-1.949), mold exposure during infancy (aOR, 1.416; 95% CI, 1.103-1.819), mold exposure during the last 12 months (aOR, 1.285; 95% CI, 1.012-1.630), and sensitization on skin prick tests (aOR, 2.596; 95% CI, 2.055-3.279). Risk factors for atopic current AR were the same as those of current AR, whereas breast-milk feeding (aOR, 0.720; 95% CI, 0.530-0.976) was a protective factor. Sensitized allergens as risk factors for current AR were Dermatophagoides pteronyssinus, Dermatophagoides farina, ragweed, mugwort, oak, alder, birch, Japanese hop, cat, and dog. CONCLUSION: The prevalences of current AR and atopic current AR were 29.0% and 18.7%, respectively. Male, sex parental AR, antibiotic use in infancy, mold exposure during the last 12 months, mold exposure during infancy, and atopic sensitization were risk factors for current AR. Breast-milk feeding was a protective factor for atopic current AR. Aeroallergen sensitization was an important risk factor for AR.
