Role of zinc finger proteins in the development and progression of hepatocellular carcinoma
DOI:10.3969/j.issn.1001-5256.2020.12.042
- VernacularTitle:锌指蛋白家族在肝细胞癌发生发展中的作用
- Author:
Junwei WEI
1
;
Caiyan ZHAO
Author Information
1. Department of Infectious Diseases, Third Hospital of Hebei Medical University, Shijiazhuang 050051, China
- Publication Type:Research Article
- Keywords:
carcinoma, hepatocellular;
zinc finger protein;
pathologic processes
- From:
Journal of Clinical Hepatology
2020;36(12):2839-2842
- CountryChina
- Language:Chinese
-
Abstract:
There are complex mechanisms in the development and progression of hepatocellular carcinoma, which have not been fully clarified at present. Zinc finger protein family is the largest transcription factor family in human genome, and more and more evidence has shown that zinc finger proteins play an important role in the development and progression of hepatocellular carcinoma and are expected to become new tumor biomarkers and therapeutic targets for hepatocellular carcinoma. This article reviews the structure and biological functions of zinc finger proteins and their role and regulatory mechanisms in hepatocellular carcinoma.
