Prevalence and risk factors of Blastocystis hominis infections among AIDS patients in Nanchang City
10.16250/j.32.1374.2020208
- VernacularTitle:南昌市艾滋病患者合并人芽囊原虫感染情况及危险因素分析
- Author:
Zhu-Hua HU
1
;
Hui-Hui CHEN
2
,
3
;
Ke QIAN
1
;
Chao-Qun NING
2
;
Guo-Hua PENG
1
;
Ying-Fang YU
2
;
Xian-Feng ZHOU
1
;
Yan-Hong CHU
2
;
Dan XU
1
;
Jia-Xu CHEN
2
;
Li-Guang TIAN
2
;
Hui LI
4
Author Information
1. Research Base of the National Key Laboratory of Infectious Disease Prevention and Control, Key Laboratory of Animal Origin and Vector-borne Infectious Diseases of Jiangxi Province, Nanchang Center for Disease Control and Prevention, Jiangxi Province, Nanchang 330038, China
2. National Institute of Parasitic Disease, Chinese Center for Disease Control and Prevention, Chinese Center for Tropical Disease Research, WHO Collaborating Center for Tropical Diseases, National Center for International Research on Tropical Diseases, Ministry of Science and Technology, Key Laboratory of Parasites and Vector Biology, National Health Commission, China
3. ▵Co-first author
4. Nanchang Municipal Health Commission, Jiangxi Province, China
- Publication Type:Journal Article
- Keywords:
Blastocystis hominis;
AIDS;
Co-infection;
Risk factor;
Nanchang City
- From:
Chinese Journal of Schistosomiasis Control
2020;32(6):577-583
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo investigate the prevalence and risk factors of Blastocystis hominis infections among AIDS patients in Nanchang City. MethodsA cross-sectional questionnaire survey was conducted among AIDS patients in Nanchang City during the period between May and September, 2016. B. hominis infection was detected in patients’stool samples using a PCR assay, and the CD4+ T cell count was measured in subjects’blood samples. In addition, the risk factors of B. hominis infection in AIDS patients were identified using univariate and multivariate logistic regression analyses. Results A survey was conducted in Nanchang City from May to September 2016. A total of 505 AIDS patients were investigated, and the prevalence of B. hominis infection was 4.16%. Univariate analysis revealed that B. hominis infection correlated with the occupation (χ2 = 8.595, P = 0.049), education level (χ2 = 14.494, P = 0.001), type of daily drinking water (χ2 = 10.750, P = 0.020), root of HIV infections (χ2 = 8.755, P = 0.026) and receiving anti-HIV therapy (χ2 = 23.083, P = 0.001) among AIDS patients, and multivariate logistic regression analysis identified daily direct drinking of tap water as a risk factor of B. hominis infections [odds ratio (OR) = 7.988, 95% confidential interval (CI): (1.160, 55.004)] and anti-HIV therapy as a protective factor of B. hominis infection [OR = 0.183, 95% CI: (0.049, 0.685)]. Conclusions The prevalence of B. hominis is 4.16% among AIDS patients in Nanchang City. Daily direct drinking of tap water is a risk factor, and anti-HIV therapy is a protective factor of B. hominis infection among AIDS patients living in Nanchang City.
