Epidemiological characteristics and interruption of 228 HBV positive pregnant women
10.3969/j.issn.1006-2483.2020.05.034
- VernacularTitle:228例HBV阳性孕妇流行病学特征及阻断分析
- Author:
Zan MAI
1
,
2
;
Jianhui FAN
3
;
Minjuan YE
3
Author Information
1. Department of Obstetrics and Gynecology, Guangzhou Eighth People'
2. s Hospital, Guangzhou, Guangdong 510060, China
3. Department of Obstetrics and Gynecology, the Third Affiliated Hospital of Sun Yat sen University, Guangzhou, Guangdong 510630, China
- Publication Type:Journal Article
- Keywords:
Hepatitis B virus;
pregnant women;
Epidemiology;
Mother-to-child transmission blocking;
Antiviral therapy
- From:
Journal of Public Health and Preventive Medicine
2020;31(5):131-134
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the epidemiological characteristics and interruption of 228 hepatitis B virus (HBV) positive pregnant women, and to provide more references for clinical education and treatment. Methods A total of 228 chronic HBV pregnant women underwent maternal-neonatal transmission blocking treatment in Third Affiliated Hospital of Sun Yat-sen University from January 2015 to April 2019 were enrolled. Self-designed follow-up questionnaires were used to collect pregnant women's data. Then the relationship of epidemiological characteristics and HBV-DNA load levels with the genotype, hepatitis B e antigen (HBeAg), and alanine aminotransferase (ALT) was analyzed, moreover, the prevention of mother-to-child transmission was also analyzed. Results A total of 228 HBV-positive pregnant women were mainly over 30 years old, with a family history of liver disease, low education level (
