Investigation of primary liver carcinoma in patients with hepatitis B and its influencing factors
10.3969/j.issn.1006-2483.2020.05.029
- VernacularTitle:乙肝患者发生原发性肝癌的调查及影响因素
- Author:
Luying LIN
1
,
2
Author Information
1. People'
2. s Hospital of Xindu District, Chengdu City, Digestive System Department, Chengdu Sichuan 610500, China
- Publication Type:Journal Article
- Keywords:
Hepatitis B;
Primary liver carcinoma;
Investigation;
Influencing factors
- From:
Journal of Public Health and Preventive Medicine
2020;31(5):114-117
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the characteristics of primary liver carcinoma (PLC) in patients with hepatitis B and to analyze the influencing factors. Methods The clinical data of 308 patients with hepatitis B in our hospital from March 2016 to March 2019 were selected to investigate the occurrence of PLC. Univariate analysis and Logistic regression were used to analyze the influencing factors of PLC in patients with hepatitis B. Results The results of this survey showed that 116 of the 308 patients with hepatitis B had PLC (37.66%). The single factor analysis showed that age, diabetes mellitus, family history of PLC, smoking, drinking, eating habits, hepatitis B virus load, e antigen, antiviral therapy, fatty liver and cirrhosis were the influencing factors of PLC in patients with hepatitis B (P < 0.05). Logistic regression analysis showed that age > 50 years old, diabetes mellitus, family history of PLC, smoking, drinking, poor diet, positive HBV load, positive e antigen, ineffective antiviral therapy, fatty liver and cirrhosis were independent risk factors for PLC in patients with hepatitis B (P < 0.05). Conclusion Patients with hepatitis B were at high risk of PLC. They were affected by various factors. It is important to strengthen the preventative care of patients over 50 years old, with diabetes mellitus, family history of PLC, smoking, drinking, poor diet, hepatitis B virus load positive, e antigen positive, ineffective antiviral therapy, fatty liver, cirrhosis and so on.
