Effect and cost-benefit of influenza vaccination for patients with chronic diseases
10.3969/j.issn.1006-2483.2020.05.006
- VernacularTitle:慢性病患者接种流感疫苗的效果与效益评价
- Author:
Minrui XU
1
;
Deren QIANG
1
;
Yingzi PAN
1
;
Suyi SHI
1
;
Jiacheng YANG
1
;
Jing ZONG
1
;
Yihong ZHOU
2
Author Information
1. Wujin Center for Disease Control and Prevention, Changzhou, Jiangsu 213164, China
2. Wujin District Health Bureau, Changzhou, Jiangsu 213164, China
- Publication Type:Journal Article
- Keywords:
CChronic diseases;
Influenza vaccine;
Cost-benefit
- From:
Journal of Public Health and Preventive Medicine
2020;31(5):21-24
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the effect and cost-benefit of influenza vaccination for patients with chronic diseases in Wujin district of Changzhou City. Methods An epidemiological quasi-experiment was employed in this study. A total of 441 patients with chronic diseases were recruited as the vaccine group and inoculated with trivalent influenza virus vaccine, while 467 patients with chronic diseases matched with the age, gender and health status of the vaccine group were selected as the control group for both baseline and follow-up investigations. Results A total of 431 subjects in the vaccine group and 460 subjects in the control group completed baseline and 1-year follow-up investigations. The incidence of influenza-like illness was 7.42% (32/431) and 14.13% (65/460) in the vaccine group and the control group, respectively, with a statistically significant difference (χ2=9.634, P=0.002). The protective rate was 47.46%, and the effect index was 1.90. The incidence of common cold was 16.94% (73/431) and 25.43% (117/460), respectively, and the difference was statistically significant (χ2=9.077, P=0.003), with a protective rate of 33.41%, and an effect index of 1.50. The incidence of chronic disease was 5.57% (24/431) and 9.35% (43/460), respectively. The difference was statistically significant (χ2=4.043, P=0.044), with a protective rate of 40.43% and an effect index of 1.68. The per capita benefit of inoculation was 675.86 yuan, and the benefit-cost ratio was 10.09:1. Conclusion Influenza vaccination for patients with chronic diseases effectively prevented the occurrence of influenza-like illness and reduced the incidence of related chronic diseases.