Differences in implant osseointegration in the jaw and femur in animal experiments
10.12016/j.issn.2096⁃1456.2021.01.009
- Author:
TANG TANG
1
,
2
;
ZHOU Anqi
1
,
2
;
YU Hui
1
,
3
;
LIU Zhenzhen
1
,
3
;
ZHANG Xinyuan
1
,
3
;
WANG Bin
1
,
3
;
ZHANG Kaiwen
1
,
2
;
XIANG Lin
1
,
3
Author Information
1. State Key Laboratory of Oral Diseases &
2. National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University
3. National Clinical Research Center for Oral Diseases, Deptartment of Oral Implantology, West China Hospital of Stomatology, Sichuan University
- Publication Type:Review
- Keywords:
dentition defect;
oral implant denture;
osseointegration;
bone metabolism;
jaw bone;
thigh bone;
embryonic development;
histomorphology
- From:
Journal of Prevention and Treatment for Stomatological Diseases
2021;29(1):57-60
- CountryChina
- Language:Chinese
-
Abstract:
The jaw and femur are commonly used sites in basic research for modeling bone defects or inserting implants. An increasing number of studies have identified that the jaw and femur indeed show great differences in embryonic development and growth, histomorphology and bone metabolism. A literature review showed that, compared with the femur, the main osteogenic pathway of the jaw may have better osteogenic ability, and its stem cells have better proliferation and osteogenic differentiation ability. However, the jaw structure is less regular, the osteogenic differentiation ability of its osteoblasts is mineralization slightly weak, and the immune cells of the jaw are more sensitive to cytokines. These may be the reasons why the osseointegration of the jaw implant is different from that of the femur in animal experiments, but its specific mechanism has not been clarified.
- Full text:基于颌骨和股骨差异的动物实验中种植体骨结合影响因素.pdf
