Cryopreservation of mouse resources
10.1186/s42826-020-00066-w
- Author:
Toru TAKEO
1
;
Satohiro NAKAO
;
Yoshiko NAKAGAWA
;
Jorge M. SZTEIN
;
Naomi NAKAGATA
Author Information
1. Division of Reproductive Engineering, Center for Animal Resources and Development, Institute of Resource Development and Analysis, Kumamoto University, 2-2-1 Honjo, Kumamoto, 860-0811, Japan
- Publication Type:Review
- From:Laboratory Animal Research
2020;36(3):152-157
- CountryRepublic of Korea
-
Abstract:
The cryopreservation of sperm and embryos is useful to efficiently archive valuable resources of genetically engineered mice. Till date, more than 60,000 strains of genetically engineered mice have been archived in mouse banks worldwide. Researchers can request for the archived mouse strains for their research projects. The research infrastructure of mouse banks improves the availability of mouse resources, the productivity of research projects, and the reproducibility of animal experiments. Our research team manages the mouse bank at the Center for Animal Resources and Development in Kumamoto University and continuously develops new techniques in mouse reproductive technology to efficiently improve the system of mouse banking. In this review, we introduce the activities of mouse banks and the latest techniques used in mouse reproductive technology.