Successful Treatment of Acquired Perforating Dermatosis in a Peritoneal Dialysis Patient Using Oral Isotretinoin
10.3904/kjm.2020.95.3.201
- Author:
Hui Seo KIM
1
;
SangHee LEE
;
MiJi LEE
;
Mihnsook JUE
;
Dong Young LEE
;
Kyoung Hyub MOON
;
Beom KIM
Author Information
1. Division of Nephrology, Department of Internal Medicine, Gwangmyeong Sungae Hospital, Gwangmyeong, Korea
- Publication Type:3
- From:Korean Journal of Medicine
2020;95(3):201-204
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Acquired perforating dermatosis (APD) triggers severe itching, and is observed most often in patients with diabetes mellitus (DM) and chronic kidney disease (CKD). Various treatments, such as topical steroids, topical and oral retinoids, allopurinol, and ultraviolet B (UVB) phototherapy, have been used. However, as the precise etiology is unknown, there are a lack of well-established treatment guidelines. We report a peritoneal dialysis patient with a diagnosis of APD who was resistant to topical steroids, phototherapy, allopurinol, and topical retinoids. Severe pruritus persisted, which compromised his ability to lead a normal life. As a final treatment option, we used oral isotretinoin and the patient experienced a dramatic improvement.
