Metabolic Outcomes of Surgery for Non-Obese Type 2 Diabetes
10.7602/jmis.2020.23.2.57
- Author:
Kyung Yul HUR
1
Author Information
1. Department of Surgery, Soonchunhyang University Seoul Hospital, Soonchunhyang University College of Medicine, Seoul, Korea
- Publication Type:REVIEW ARTICLE
- From:Journal of Minimally Invasive Surgery
2020;23(2):57-62
- CountryRepublic of Korea
- Language:English
-
Abstract:
The most plausible contributing factor to non-obese type 2 diabetes may be imbalanced incretin release from the intestinal epithelium in response to nutrients. Rerouting intestinal continuity through bypass surgery to modulate incretin release is therefore a reasonable treatment. We believe that a major determinant of metabolic outcomes is entire duodenal exclusion without leaving any duodenal epithelium and exclusion of sufficient length of jejunum. More importantly, the procedure should be implemented with safety and without sequelae. To achieve this, we invented a novel procedure with acceptable surgical safety and excellent and durable metabolic outcomes. Post-surgical intestinal adaptation should be considered to achieve successful outcomes.
