Worsening of Psychotic Symptoms in Patients with Chronic Schizophrenia after Switching to or Combining Aripiprazole and Aripiprazole Monthly (Abilify Maintena)
10.4306/jknpa.2020.59.2.166
- Author:
MyeongHyun Michelle PARK
1
;
Su Ryong KIM
;
Woong HAHM
;
In Ho PAIK
Author Information
1. Department of Psychiatry, Keyo Hospital, Uiwang, Korea
- Publication Type:ORIGINAL ARTICLE
- From:Journal of Korean Neuropsychiatric Association
2020;59(2):166-169
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Objectives:Aripiprazole is an antipsychotic that functions as a partial agonist in hypodopaminergic states and a dopamine antagonist in hyperdopaminergic states.
Methods:This paper reports a series of five clinical cases of worsening psychotic symptoms in schizophrenic patients related to the initiation of aripiprazole, oral and injection, as combination therapy.
Results:In all five cases, the switching of aripiprazole improved the psychotic symptoms.
Conclusion:Even with the suggestive relationship between aripiprazole therapy and the worsening of psychotic symptoms, further research is needed.
