Decreased Hippocampal Metabolism in Amnestic Mild Cognitive Impairment: Positron Emission Tomography Study
- Author:
Chan hum PARK
1
;
Young Min LEE
;
JeMin PARK
;
Byung Dae LEE
;
EunSoo MOON
;
Hee Jeong JEONG
;
Soo Yeon KIM
;
Kang Yoon LEE
;
Hwagyu SUH
;
Hye Kyung PARK
;
Hak-Jin KIM
;
Kyoungjune PARK
;
Chi-Woong MUN
;
Young-In CHUNG
Author Information
1. Departments of Psychiatry, Pusan National University Hospital, Busan, Korea
- Publication Type:Original Article
- From:Journal of Korean Geriatric Psychiatry
2020;24(1):37-41
- CountryRepublic of Korea
- Language:0
-
Abstract:
Objective:Little is known about factors influencing of hippocampal metabolism (HM) in mild cognitive impairment (MCI). Our objective was to determine whether HM in patients with amnestic MCI (aMCI) is decreased than non-amnestic MCI (naMCI).
Methods:Overall, 32 MCI patients underwent 18F-fluorodeoxyglucose-positron emission tomography. They were characterized as aMCI (n=18) or naMCI (n=14) according to comprehensive neuropsychological criteria. Analysis of variances were used to assess differences on HM between aMCI and naMCI after controlling age, sex, education and Korean version of Mini Mental Status Examination.
Results:We found that HM was more decreased in aMCI than naMCI. This result was not changed after controlling hippocampal volume.
Conclusion:Our findings suggest that aMCI is associated with decreased HM in MCI.
