Anti-LGI1 Antibody Limbic Encephalitis Associated with Hepatocellular Carcinoma
- Author:
Seokhong CHOI
1
;
Du Hwan KIM
;
Hyun Joon LEE
;
Dong Jin SHIN
Author Information
- Publication Type:증례
- From:Journal of the Korean Neurological Association 2020;38(4):272-275
- CountryRepublic of Korea
- Language:Korean
- Abstract: Anti-leucine-rich glioma inactivated-1 (LGI1) antibody has been known as the most common antibody in autoimmune limbic encephalitis. We report a case of a 63-year-old woman who presented with repetitive memory impairment. She was diagnosed with anti-LGI1 limbic encephalitis by clinical symptoms, magnetic resonance imaging, electroencephalography, and antibody test. Hepatocellular carcinoma (HCC) was discovered incidentally. Clinical seizures were completely controlled after hepatic segmentectomy without immunotherapy. This is the first case report showing the relationship between HCC and anti-LGI1 limbic encephalitis.
