Etiology and Antimicrobial Susceptibility of Bacterial Pathogens Causing Community-Acquired Urinary Tract Infection at a Tertiary-care Hospital.
- Author:
Jeong Hwan SHIN
1
;
Hye Ran KIM
;
Hi Ryune LEE
;
Jae Il CHUNG
;
Kweonsik MIN
;
Chi Sook MOON
;
Seong Mi RYU
;
Jeong Nyeo LEE
Author Information
1. Department of Laboratory Medicine, College of Medicine, Inje University, Korea. jhsmile@inje.ac.kr
- Publication Type:Original Article
- Keywords:
Community-acquired infection;
Urinary tract infection;
Etiology;
Antibiotic resistance
- MeSH:
Ampicillin;
beta-Lactamases;
Ciprofloxacin;
Coagulase;
Community-Acquired Infections;
Drug Resistance, Microbial;
Enterobacteriaceae;
Enterococcus faecalis;
Escherichia coli;
Female;
Gentamicins;
Humans;
Klebsiella pneumoniae;
Male;
Pneumonia;
Prevalence;
Pseudomonas aeruginosa;
Staphylococcus aureus;
Trimethoprim, Sulfamethoxazole Drug Combination;
Urinary Tract Infections*;
Urinary Tract*
- From:Korean Journal of Clinical Microbiology
2005;8(2):142-147
- CountryRepublic of Korea
- Language:English
-
Abstract:
BACKGROUND: Resistant organisms are now a growing and frequent problem in community-acquired infections. There is little information on the etiology and antimicrobial susceptibility patterns of community-acquired urinary tract infection (CA-UTI) at a tertiary-care hospital. METHODS: We evaluated the distribution of etiological organisms with their antimicrobial susceptibility patterns of CA-UTI in the patients visiting a tertiary-care hospital during the period of three years from 2001 through 2003. RESULTS: In total, 1,753 bacterial isolates yielded a significant growth as pathogens of CA-UTI in this study. The most common pathogen was Escherichia coli (38.3%), followed by Pseudomonas aeruginosa (10.8%), Enterococcus faecalis (7.3%), Klebsiella pneumoniae (6.4%), coagulase negative staphylococci (CoNS) (5.4%) and Staphylococcus aureus (5.2%). The prevalence of E. coli was significantly higher in females (P < 0.001), whereas P. aeruginosa, E. faecalis, and S. aureus were significantly more common in male group (P < 0.001). The susceptibility rate of E. coli was 26.0% to ampicillin, 65.8% to gentamicin, 51.3% to co-trimoxazole, and 62.5% to ciprofloxacin. The susceptibility patterns of Enterobacteriaceae other than E. coli were different from those of E. coli. Extended spectrum beta-lactamase was detected in 7.9% of E. coli and 15.6% of K. pneumoniae. CONCLUSION: This study demonstrates a diversity of etiological organisms and a high rate of resistance to commonly used antimicrobials of CA-UTI in patients visiting a tertiary-care hospital.
