Renal intravascular large B cell lymphoma: the first case report in Korea and a review of the literature
- Author:
Moonsik KIM
1
;
Haerim CHUNG
;
Woo Ick YANG
;
Hyeon Joo JEONG
Author Information
- Publication Type:Case Study
- From:Journal of Pathology and Translational Medicine 2020;54(5):426-431
- CountryRepublic of Korea
- Language:0
- Abstract: Herein, we describe the first case of renal intravascular large B cell lymphoma in Korea occurring in a 66-year-old female. She presented with mild fever and dyspnea. On physical and laboratory evaluations, hemophagocytic lymphohistiocytosis was suspected, but the bone marrow biopsy results were unremarkable. During the work-up, massive proteinuria developed, which led to a renal biopsy. The renal architecture was relatively well-preserved, but the glomeruli were hypercellular with the infiltration of atypical, large lymphoid cells with increased nucleus-cytoplasm ratio and clumped chromatin. Similar cells were also present in the peritubular capillaries. The tumor cells exhibited membranous staining for CD20 and CD79a. After the diagnosis of intravascular large B cell lymphoma, the patient received rituximab-based chemotherapy under close follow-up.
