Pituitary Apoplexy due to Pituitary Adenoma Infarction.
10.3340/jkns.2008.43.5.246
- Author:
Joo Pyung KIM
1
;
Bong Jin PARK
;
Sung Bum KIM
;
Young Jin LIM
Author Information
1. Department of Neurosurgery, Kyung Hee University Hospital, Seoul, Korea. hyunsong@khmc.or.kr
- Publication Type:Case Report
- Keywords:
Pituitary apoplexy;
Pituitary adenoma infarction
- MeSH:
Adrenocorticotropic Hormone;
Hemorrhage;
Humans;
Infarction;
Pituitary Apoplexy;
Pituitary Gland;
Pituitary Neoplasms
- From:Journal of Korean Neurosurgical Society
2008;43(5):246-249
- CountryRepublic of Korea
- Language:English
-
Abstract:
Cause of pituitary apoplexy has been known as hemorrhage, hemorrhagic infarction or infarction of pituitary adenoma or adjacent tissues of pituitary gland. However, pituitary apoplexy caused by pure infarction of pituitary adenoma has been rarely reported. Here, we present the two cases pituitary apoplexies caused by pituitary adenoma infarction that were confirmed by transsphenoidal approach (TSA) and pathologic reports. Pathologic report of first case revealed total tumor infarction of a nonfunctioning pituitary macroadenoma and second case partial tumor infarction of ACTH secreting pituitary macroadenoma. Patients with pituitary apoplexy which was caused by pituitary adenoma infarction unrelated to hemorrhage or hemorrhagic infarction showed good response to TSA treatment. Further study on the predisposing factors of pituitary apoplexy and the mechanism of infarction in pituitary adenoma is necessary.