Serrated Polyposis Syndrome with a Synchronous Colon Adenocarcinoma Treated by an Endoscopic Mucosal Resection
10.4166/kjg.2020.76.3.159
- Author:
Sang Hoon LEE
;
Sung Joon LEE
;
Sung Chul PARK
;
Seung-Joo NAM
;
Myeong Ho KANG
;
Tae Suk KIM
;
Seung Koo LEE
- Publication Type:Case Report
- From:The Korean Journal of Gastroenterology
2020;76(3):159-163
- CountryRepublic of Korea
-
Abstract:
Serrated polyposis syndrome (SPS) can transform to malignant lesions through the sessile serrated pathway and traditional serrated pathway. These pathways may cause rapid neoplastic progression compared to the adenoma-carcinoma sequence, which may cause interval colorectal cancer. The authors experienced a case of SPS with a synchronous colon adenocarcinoma that was treated with an endoscopic mucosal resection. In pathology reviews, other parts of the adenocarcinoma showed sessile serrated adenoma. Therefore, patients with SPS have a potential for malignant transformation, highlighting the need for strict colonoscopy surveillance starting at the time of SPS diagnosis.