Post-colonoscopy Colorectal Cancer: Causes and Prevention of Interval Colorectal Cancer
10.4166/kjg.2020.75.6.314
- Author:
Jong Yoon LEE
1
;
Jong Hoon LEE
Author Information
1. Department of Gastroenterology, Dong-A University Hospital, Busan, Korea
- Publication Type:REVIEW ARTICLE
- From:The Korean Journal of Gastroenterology
2020;75(6):314-321
- CountryRepublic of Korea
-
Abstract:
Colorectal cancer (CRC) is the third most commonly diagnosed cancer and the fourth leading cause of cancer death in the worldwide. Colonoscopy is the gold standard for screening and surveillance of CRC. Removing adenomas by colonoscopy has lowered the incidence and mortality of CRC. However, colonoscopy is imperfect for detection of colorectal neoplasia. After a colonoscopy that is negative for malignancy, CRC can be diagnosed. These are termed as post-colonoscopy CRC (PCCRC). The proportion of PCCRC, among all CRC was reported to be 1.8% to 9.0%. It occurred 2.4 times more in the right colon than in the left colon. The causes of PCCRC are missed lesions, incomplete resection, and new lesions. Among these causes, missed lesion and incomplete resection are procedural factors and preventable. Therefore, it is necessary to improve the quality of colonoscopy to minimize the occurrence of PCCRC.
