Metachronous Development of Peritoneal Carcinomatosis in a Patient with Autoimmune Pancreatitis
10.4166/kjg.2020.75.6.356
- Author:
Kyu Won LEE
1
;
Jae Hyuck CHANG
;
Jeana KIM
;
Tae Ho KIM
;
Chang Whan KIM
;
Jae Kwang KIM
;
Sok Won HAN
Author Information
1. Departments of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea
- Publication Type:CASE REPORT
- From:The Korean Journal of Gastroenterology
2020;75(6):356-361
- CountryRepublic of Korea
-
Abstract:
Autoimmune pancreatitis (AIP) is a rare and unique type of chronic pancreatitis. The prognosis of AIP, particularly when associated with pancreatic cancer or a related malignancy, is not known. Only a few cases, where metachronous pancreas-related cancer developed during follow-up, have been reported. Most of these patients either underwent surgery or steroid therapy. This paper reports a case of a 66-year-old woman with untreated type I AIP who developed peritoneal carcinomatosis more than 2 years later. Initially, the patient had a markedly elevated serum IgG4 level and a diffuse, infiltrative mass-like lesion in the pancreatic head, in which the biopsy results were consistent with type I AIP. The patient was not treated with steroids because of a cerebellar infarction. Twenty-eight months after the diagnosis of AIP, peritoneal carcinomatosis developed without noticeable changes in the pancreas from the initial findings.
