Anaphylaxis induced by sugammadex and sugammadex-rocuronium complex -a case report-
- Author:
Shu Chung CHOI
1
;
Sangbin HAN
;
Jueun KWAK
;
Ji Yung LEE
Author Information
- Publication Type:Case Report
- From:Korean Journal of Anesthesiology 2020;73(4):342-346
- CountryRepublic of Korea
-
Abstract:
Background: In sugammadex-induced anaphylaxis, sugammadex and/or sugammadex-rocuronium complex have possible allergenic epitope. Case: We report a case of sugammadex-induced anaphylaxis during general anesthesia in a 60-year-old male undergoing orthopedic hand surgery, manifesting as profound hypotension and urticaria. The timing of onset was closely associated with sugammadex administration. The patient recovered after extensive therapy including fluid, epinephrine, other vasopressors, steroid, and antihistamine administration. By intradermal skin test which was done at four weeks after anaphylaxis, we confirmed positive reactions to both sugammadex and sugammadex-rocuronium complex.
Conclusions: This is a rare case of sugammadex-induced anaphylaxis that both sugammadex and sugammadex-rocuronium complex were confirmed as allergenic epitopes.
