A Study of Clinical Manifestations of Gastrointestinal Symptoms in Children with Henoch-Schnlein Purpura.
- Author:
Se Whung OH
1
;
Jae Hyung CHOE
;
Yong Joo KIM
Author Information
1. Department of Pediatrics, Hanyang University College of Medicine, Seoul, Korea. kyjoo@hanyang.ac.kr
- Publication Type:Original Article
- Keywords:
Henoch-Schnlein purpura;
Gastrointestinal symptoms;
Children;
GI endoscopy;
Stool occult blood
- MeSH:
Abdominal Pain;
Child*;
Colitis;
Diagnosis;
Diarrhea;
Duodenal Ulcer;
Duodenitis;
Endoscopy;
Gastritis;
Hemorrhage;
Humans;
Joints;
Medical Records;
Nausea;
Occult Blood;
Purpura*;
Recurrence;
Retrospective Studies;
Scrotum;
Skin;
Ultrasonography;
Vomiting
- From:Korean Journal of Pediatric Gastroenterology and Nutrition
2006;9(2):183-192
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: This study was undertaken to evaluate the factors correlated with the clinical course and outcome in patients of Henoch-Schnlein Purpura. METHODS: The medical records of 104 children diagnosed with Henoch-Schnlein Purpura (HSP) from January 1996 to April 2006 were reviewed retrospectively. The patients were divided into two groups: patients with Gastrointestinal (GI) symptoms and those without GI symptoms. When there were joint, scrotum, and renal symptoms except for skin lesion in whole HSP, those patients were excluded. The history of acute infection, duration of admission, treatment requirement, recurrence of HSP, CBC, stool occult blood test, abdominal ultrasonographic findings and GI endoscopic findings were reviewed. RESULTS: Among 104 patients, patients with GI symptoms included 66 cases (63.5%), those without GI symptoms accounted for 38 cases (36.5%). GI symptoms included: abdominal pain in 57 cases (54.8%), vomiting 21 cases (20.2%), GI bleeding 5 cases (4.8%), nausea 3 cases (2.9%) and diarrhea 3 case (2.9%). Positive GI symptoms and GI mucosal lesions on GI endoscopy had a statistically significant correlation with increased admission duration, treatment requirement, recurrence of HSP, and positive stool occult blood. Six cases with small intestinal wall thickening were noted on abdominal ultrasonography. Six cases of hemorrhagic gastritis and hemorrhagic duodenitis, 3 cases of duodenal ulcer, 3 cases of hemorrhagic gastritis and duodenal ulcer, 2 cases of hemorrhagic duodenitis and colitis, and 1 case of colitis were noted on GI endoscopy. CONCLUSION: These results suggest that GI endoscopic examination may be helpful for the diagnosis and treatment of children with HSP.
