Evaluation of a domestic second generation platelet storage container.
- Author:
Kyou Sup HAN
1
;
Mun Jeong KIM
;
Hyun Ok KIM
Author Information
1. Department of Clinical Pathology, Seoul National University College of Medicine, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
PVC-TOTM;
Tri(2-ethylhexyl) phthalate;
Second generation platelet storage container
- MeSH:
beta-Thromboglobulin;
Blood Platelets*;
Dihydroergotamine;
Hydrogen-Ion Concentration;
Korea;
Lactic Acid;
Osmotic Pressure;
Plastics;
Platelet Activation;
Platelet Count;
Polyvinyls
- From:Korean Journal of Blood Transfusion
1998;9(2):253-258
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: Polyvinyl (PVC) plastic container plasticized with di-(2-ethylhexyl) phthalate (DEHP) has been used for the storage of platelet concentrates for five days in Korea. Authors evaluated a second generation platelet storage container plasticized with tri (2-ethylhexyl) phthalate (TOTM) which was recently produced by Green Cross Medical Corp.(Korea). METHODS: 30 units of platelet concentrates were stored in TOTM-PVC container at 22'C in a flatbed agitator. Samples were taken at day 1,3,5, and 7 from the containers and tested for platelet count, MPV, PDW, pH, HCO3-,LDH, lactate, hypotonic shock response and beta-thromboglobulin (beta-TG). Electron microscopic examination was also performed. RESULTS: The number and functions of platelets were well preserved during storage. pH was maintained above 6.8 and any evidence for platelet activation was minimal. CONCLUSION: The TOTM-PVC second generation platelet storage container recently produced by the Green Cross Medical Corp.(Korea) was able to preserve platelets for at least five days without significant storage lesions.