A Case of Vanishing Bile Duct Syndrome after Drug-Induced Liver Injury Caused by Pelubiprofen
10.3349/ymj.2020.61.12.1060
- Author:
Haein BAK
1
;
Hayeon KIM
;
Sieun LEE
;
Yoonseok LEE
;
Soo-Min BANG
;
Young-Sun LEE
Author Information
1. Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea
- Publication Type:Case Report
- From:Yonsei Medical Journal
2020;61(12):1060-1063
- CountryRepublic of Korea
- Language:English
-
Abstract:
Vanishing bile duct syndrome (VBDS) is a rare disease characterized by ductopenia and cholestasis, and is linked to immunological damage to the bile duct system. VBDS can be triggered by infection, ischemia, autoimmune diseases, adverse drug reactions, and humoral factors associated with malignancy. A few cases of VBDS associated with nonsteroidal anti-inflammatory drug-related drug-induced liver injury (DILI) have been reported. Here, we report a case of a 29-year-old patient who developed DILI that progressed to VBDS after the administration of pelubiprofen.
