A Case of Breakthrough COVID-19 during Hydroxychloroquine Maintenance
10.3346/jkms.2020.35.e231
- Author:
Byeong Yun AHN
1
;
Chang Kyung KANG
;
Jong Do SEO
;
Pyoeng Gyun CHOE
;
Sang Hoon SONG
;
Wan Beom PARK
;
Sang Won PARK
;
Nam Joong KIM
;
Myoung-don OH
Author Information
1. Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea
- Publication Type:Case Report
- From:Journal of Korean Medical Science
2020;35(24):e231-
- CountryRepublic of Korea
- Language:0
-
Abstract:
There have been controversies on the prophylactic effect of hydroxychloroquine against severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). We describe a patient, 60-year old Korean woman, with coronavirus disease 2019 (COVID-19) who had been taking hydroxychloroquine for 6 months. Her serum and saliva concentrations of hydroxychloroquine were 280 μg/L and 4,890 μg/L, respectively. The present case raises concerns on hydroxychloroquine's role as a prophylactic agent for COVID-19.