The promotion of precise diagnosis and treatment of thyroid cancer by mass spectrometry-based high throughput proteomics technologies
DOI：10.3872/j.issn.1007-385x.2020.11.001
- VernacularTitle:基于质谱的高通量蛋白质组学技术对甲状腺癌精准诊疗的推动
- Author:
LIANG Nan
1
;
RAN Bingbing
;
SUN Hui
Author Information
1. Department of Thyroid Surgery, China-Japan Union Hospital of Jilin University, Jilin Provincial Key Laboratory of Surgical Translational Medicine, Jilin Provincial Engineering Laboratory of Thyroid Disease Prevention and Control, Changchun 130033, Jilin, China
- Publication Type:Journal Article
- Keywords:
甲状腺癌；质谱；蛋白质组学；生物标志物；精准诊疗
- From:
Chinese Journal of Cancer Biotherapy
2020;27(11):1199-1205
- CountryChina
- Language:Chinese
-
Abstract:
甲状腺癌是常见的内分泌恶性肿瘤，发病率逐年增加。深入了解甲状腺癌发生发展机制对提高诊断准确性、进行精准风险分层和实现个性化治疗至关重要。近年来，随着质谱相关技术的不断发展，基于不同标本类型（细胞、组织、血清和尿液）的多种蛋白质组学分析方法已被广泛应用于甲状腺癌的研究中，从阐明发病机制、诊断分型、预测预后和靶向治疗等方面积极地推动了甲状腺癌精准诊疗的发展。
- Full text:20201101.pdf
