Optimal numbers of mature oocytes to produce at least one or multiple top-quality day-3 embryos in normal responders
- Author:
Yoo Jin SHIM
1
;
Yeon Hee HONG
;
Seul Ki KIM
;
Byung Chul JEE
Author Information
- Publication Type:Original Article
- From:Clinical and Experimental Reproductive Medicine 2020;47(3):221-226
- CountryRepublic of Korea
- Language:English
-
Abstract:
Methods:We selected 210 fresh IVF cycles performed in 170 infertile women at a single center from January 2014 to November 2019. Four to 14 (total) oocytes were obtained in all cycles after conventional ovarian stimulation. A receiver operating characteristic curve analysis was performed to find the moderate and extreme cutoff numbers of mature oocytes that would produce ≥1, ≥2, ≥3, ≥4, and ≥5 top-quality embryos.
Results:The cutoff number of mature oocytes was significantly correlated with the number of top-quality embryos (r =0.467, p =0.000). The moderate cutoff number of mature oocytes was ≥3, ≥5, ≥5, ≥6, and ≥6 for obtaining ≥1, ≥2, ≥3, ≥4, and ≥5 top-quality embryos, respectively. The extreme cutoff number of mature oocytes was ≥9, ≥9, ≥10, ≥10, and ≥11 for obtaining ≥1, ≥2, ≥3, ≥4, and ≥5 top-quality embryos, respectively.
Conclusion:We present the optimal cutoff numbers of mature oocytes that would yield ≥1, ≥2, ≥3, ≥4, and ≥5 top-quality embryos with 95% specificity. Our findings could help infertility clinicians to set target mature oocyte numbers in women undergoing stimulated IVF cycles.
