Clinical Study of 25 Cases of Erythema Dyschromicum Perstans.
- Author:
Seung Hun LEE
;
Seung Kyung HANN
;
Yoon Kee PARK
;
Sung Nack LEE
- Publication Type:Original Article
- Keywords:
Erythema dyschromicum perstans;
Clinical study
- MeSH:
Age of Onset;
Erythema*;
Extracellular Space;
Humans;
Incidence;
Melanosomes;
Neck;
Shoulder
- From:Korean Journal of Dermatology
1986;24(6):757-765
- CountryRepublic of Korea
- Language:English
-
Abstract:
We studied 25 cases of clinically diagnosed erythema dyschrornicum perstans (EDP) who were seen in our clinic within 11-year period, from 1975 through 1985, and compared light and electron microscopic findings, and direct immunoflunrescence findings. The results are summarized as follows: 1. There were 16 males(64%) and 9 females(36%). The peak age incidence was in the second decade. 2. The mean age of onset was 18 years(M: 16. 6, F: 19. 4) and the rnean duration was 1.8 years(M: 2.6, F: 1.0). 3. The annual incidence increased from 1981 and was peaked in 1985. 4. The most commonly involvement site was the trunk(92%), the least common involvement(4%) was one of the face, neck, and shoulder combined. 5. The histopathologic findings in most patients shows focal vacuolization of the basal cell layer, pigment incontinence, dermal melanophages. 6. Electron microscopic findings of five patients consist of vauoles with abundant melanosomes in the basal cells, widened intercellular spaces and dermal melanophages.