Evaluating Spinal Canal Lesions Using Apparent Diffusion Coefficient Maps with Diffusion-Weighted Imaging
- Author:
Hirohito KANAMOTO
1
;
Masaki NORIMOTO
;
Yawara EGUCHI
;
Yasuhiro OIKAWA
;
Sumihisa ORITA
;
Kazuhide INAGE
;
Koki ABE
;
Masahiro INOUE
;
Hideyuki KINOSHITA
;
Tomotaka UMIMURA
;
Koji MATSUMOTO
;
Yoshitada MASUDA
;
Takeo FURUYA
;
Masao KODA
;
Yasuchika AOKI
;
Atsuya WATANABE
;
Kazuhisa TAKAHASHI
;
Seiji OHTORI
Author Information
- Publication Type:Clinical Study
- From:Asian Spine Journal 2020;14(3):312-319
- CountryRepublic of Korea
- Language:0
-
Abstract:
Methods:We performed 3T MRI in 10 healthy volunteers and 13 patients with LSS. The ADC values in the spinal canal were evaluated at 46 vertebrae (L4/5 and L5/S1 for each participant), and the reduced and conventional fields of view were compared.
Results:The ADC values were 2.72±0.12 at L4/5 in healthy volunteers, 2.76±0.19 at L5/S1 in healthy volunteers, 1.77±0.58 at L4/5 in patients with LSS, and 2.35±0.29 at L5/S1 in patients with LSS. The ADC value at L4/5 in patients with LSS was significantly lower than that at L5/S1 in patients with LSS and that at L4/5 and L5/S1 in healthy volunteers (p <0.05). With an ADC cutoff value of 2.46 to identify LSS, this approach provided an area under the curve of 0.81, sensitivity of 0.92, and specificity of 0.76 (p <0.05).
Conclusions:Preoperative examination using ADC maps permits visualization and quantification of spinal canal lesions, thus proving the utility of ADC maps in the selection of decompression surgery for LSS.
