The efficacy of 18F-FDG PET/CT in the preoperative evaluation of pancreatic lesions
10.4174/astr.2020.98.4.184
- Author:
Atilgan Tolga AKCAM
1
;
Zafer TEKE
;
Ahmet Gokhan SARITAS
;
Abdullah ULKU
;
Isa Burak GUNEY
;
Ahmet RENCUZOGULLARI
Author Information
1. Department of General Surgery, Faculty of Medicine, Cukurova University, Adana, Turkey
- Publication Type:ORIGINAL ARTICLE
- From:Annals of Surgical Treatment and Research
2020;98(4):184-189
- CountryRepublic of Korea
- Language:English
-
Abstract:
Purpose:Since the treatment strategy for benign and malignant pancreatic lesions differ, we aimed to evaluate the clinical value of PET/CT in the diagnosis and management of pancreatic lesions.
Methods:Ninety patients who had a histologically confirmed pancreatic lesion were studied. Receiver operating characteristic (ROC) curve analysis was used to investigate the ability of PET/CT to differentiate malignant lesions from benign tumors.
Results:The malignant and benign groups comprised 64 and 26 patients, respectively. Despite the similarity in the size of primary tumors (P = 0.588), the mean maximum standardized uptake values (SUVmax) obtained from PET/CT imaging were significantly higher in malignant lesions (9.36 ± 5.9) than those of benign tumors (1.04 ± 2.6, P < 0.001). ROC analysis showed that the optimal SUVmax cutoff value for differentiating malignant lesions (to an accuracy of 91%; 95% confidence interval, 83%–98%) from benign tumors was 3.9 (sensitivity, 92.2%; specificity, 84.6%).
Conclusion:PET/CT evaluation of pancreatic lesions confers advantages including fine assessment of malignant potential with high sensitivity and accuracy using a threshold SUVmax value of 3.9.
