99mTc-MIBI scan in mammary Pagets disease: a case report.
10.3346/jkms.1999.14.6.675
- Author:
Sehwan HAN
1
;
Jung Sook KIM
;
Bang Soon KIM
;
Il Hyang KOH
;
Kyeongmee PARK
Author Information
1. Department of Surgery, Inje University Sanggye Paik Hospital, Seoul, Korea. shwhan@unitel.co.kr
- Publication Type:Case Report
- Keywords:
Breast;
Paget's disease, mammary;
Technetium Tc 99m Sestamibi;
Diagnosis
- MeSH:
Breast Neoplasms/radionuclide imaging*;
Breast Neoplasms/pathology;
Case Report;
Female;
Human;
Middle Age;
Nipples/pathology;
Paget's Disease, Mammary/radionuclide imaging*;
Paget's Disease, Mammary/pathology;
Skin/pathology;
Technetium Tc 99m Sestamibi/diagnostic use*
- From:Journal of Korean Medical Science
1999;14(6):675-678
- CountryRepublic of Korea
- Language:English
-
Abstract:
Technetium-99m methoxyisobutylisonitrile (99mTc-MIBI) uptake is known to be increased in breast cancer because of increased blood flow from angiogenesis and heightened metabolism. We performed a 99mTc-MIBI scan in a patient with mammary Paget's disease. The patient had underlying invasive cancer in the same side of the breast. 99mTc-MIBI scan exhibited a scintigraphic image of the uptake from the invasive cancer lesion located deeply in the breast toward the epidermis. 99mTc-MIBI showed an uptake in the deeply located invasive cancer lesion as well as nipple lesion. Especially, the delayed phase of Tc-MIBI scan demonstrated the tumor site more accurately. In conclusion, 99mTc-MIBI scan could be a useful adjunct to clinical decision making in the management of Paget's disease of the breast.
