Acquired Reactive Perforating Collagenosis of Diabetes Mellitus and Chronic Renal Failure.
10.5021/ad.1990.2.1.43
- Author:
Tae Jin CHUN
;
Myeung Nam KIM
;
Kye Yong SONG
;
Byung In RO
;
Chin Yo CHANG
- Publication Type:Case Report
- Keywords:
Chronic renal failure;
Diabetes mellitus;
Reactive perforating collagenosis
- MeSH:
Basophils;
Collagen;
Depression;
Dermis;
Diabetes Mellitus*;
Epidermis;
Extremities;
Humans;
Kidney Failure, Chronic*;
Middle Aged;
Peas;
Pruritus;
Renal Dialysis;
Skin
- From:Annals of Dermatology
1990;2(1):43-46
- CountryRepublic of Korea
- Language:English
-
Abstract:
We report, herein, a case of reactive perforating collagenosis in a 52-year-old man with diabetes mellitus and chronic renal failure on hemodialysis. He had multiple, pinhead to pea sized, round or oval shaped, central umbilicated papules on the face, trunk, and extremities for 3 months duration. The papules developed after scratching due to pruritus. Histopathologic examination showed a cup-shaped depression of the epidermis filled with parakeratotic material, necrobiotic collagen and inflammatory cells. At the base of the depression, the epidermis showed interruption through which basophilic bundles of collagen ex-tend in a vertical direction from the dermis. The skin lesions improved after treatment with oral antihistaminics:
