Hyalinizing Clear Cell Carcinoma of the Soft Palate - A Case Report

Sharifah Intan Safuraa; Sethu Subha; Muhamad Doi; Sellymiah Adzman

Return

Hyalinizing Clear Cell Carcinoma of the Soft Palate - A Case Report

Author: Sharifah Intan Safuraa ¹ ; Sethu Subha ² ; Muhamad Doi ³ ; Sellymiah Adzman ⁴
Author Information

1. Department of Otorhinolaryngology- Head and Neck Surgery, National University of Malaysia Medical Centre, Cheras, 56000, Kuala Lumpur, Malaysia
2. Department of Otorhinolaryngology-Head and Neck Surgery, University Putra Malaysia, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400, Serdang, Selangor
3. Department of Otorhinolaryngology-Head and Neck Surgery, Serdang Hospital, 43000, Serdang, Selangor, Malaysia
4. Department Of Pathology, Hospital Serdang, 43000, Kajang, Selangor
Publication Type:Case Reports
Keywords: Hyalinizing clear cell carcinoma, Minor salivary glands, Immunohistochemistry, Palate
From:Malaysian Journal of Medicine and Health Sciences 2020;16(No.1):333-4
CountryMalaysia
Language:English
Abstract: Hyalinizing clear cell carcinoma presents as a painless submucosal mass commonly located at the palate and base of tongue. It is a rare tumour and has often been misdiagnosed for other more common tumours with clear cytoplasm, such as acinic cell carcinoma, clear cell oncocytoma or mucoepidermoid carcinoma. HCCC has been reported as a low grade malignant tumour with a high rate of cervical metastases. Due to its rarity, there is no treatment protocol. However, the treatment of choice is wide local excision and the neck disease is treated with neck dissection or radiotherapy or both with no conclusive outcome as incidence is too low or underreported with no long term follow up. Our case highlights the diagnosis difficulties in such rare cases, and the need for longer follow up post excision to determine outcome and recurrence rates.
Full text:11.2020my0611.pdf