Management of prediabetes in Malaysian population: An experts’ opinion

Mafauzy Mohamed; Ee Ming Khoo; Zanariah Hussein; Nor Shaffinaz Yusoff Azmi; Guan Jian Siah; Feisul Idzwan Mustapha; Noor Lita Adam; Azhari Rosman; Beng Tian Lee; Siew Hui Foo; Nagammai Thiagarajan; Nik Mazlina Mohammad; Kevin Moses; Hannah Loke

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Management of prediabetes in Malaysian population: An experts’ opinion

Author: Mafauzy Mohamed ¹ ; Ee Ming Khoo ² ; Zanariah Hussein ³ ; Nor Shaffinaz Yusoff Azmi ⁴ ; Guan Jian Siah ⁵ ; Feisul Idzwan Mustapha ⁶ ; Noor Lita Adam ^{7
,

8} ; Azhari Rosman ⁹ ; Beng Tian Lee ¹⁰ ; Siew Hui Foo ¹¹ ; Nagammai Thiagarajan ¹² ; Nik Mazlina Mohammad ; Kevin Moses ¹³ ; Hannah Loke ¹³
Author Information

1. Medicine Department, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, Kelantan, Malaysia
2. Department of Primary Care Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia
3. Endocrine Unit, Department of Medicine, Hospital Putrajaya, Putrajaya, Malaysia
4. Endocrine Unit, Department of Medicine, Hospital Sultanah Bahiyah, Alor Setar, Kedah, Malaysia
5. National Heart Institute, Kuala Lumpur, Malaysia
6. Disease Control Division (Non-Communicable Diseases Sector), Ministry of Health, Ministry of Health, Putrajaya, Malaysia
7. Endocrine Unit, Department of Medicine, Hospital Tuan Ja&rsquo
8. afar, Negeri Sembilan Darul Khusus, Malaysia
9. Medicare Clinic, Mid Valley Megamall, Mid Valley City, Kuala Lumpur, Malaysia
10. Selayang Hospital, Selangor, Malaysia
11. Klinik Kesihatan Kuala Lumpur, Kuala Lumpur, Malaysia
12. Klinik Kesihatan Kelana Jaya, Petaling Jaya, Selangor, Malaysia
13. Medical Department, Merck Sdn Bhd, Bandar Sunway, Selangor, Malaysia
Publication Type:Other Types
From: The Medical Journal of Malaysia 2020;75(4):419-427
CountryMalaysia
Language:English
Abstract: Introduction: Prediabetes, typically defined as blood glucose levels above normal but below diabetes thresholds, denotes a risk state that confers a high chance of developing diabetes. Asians, particularly the Southeast Asian population, may have a higher genetic predisposition to diabetes and increased exposure to environmental and social risk factors. Malaysia alone was home to 3.4 million people with diabetes in 2017; the figure is estimated to reach 6.1 million by 2045. Developing strategies for early interventions to treat prediabetes and preventing the development of overt diabetes and subsequent cardiovascular and microvascular complications are therefore important. Methods: An expert panel comprising regional experts was convened in Kuala Lumpur, for a one-day meeting, to develop a document on prediabetes management in Malaysia. The expert panel comprised renowned subject-matter experts and specialists in diabetes and endocrinology, primary-care physicians, as well as academicians with relevant expertise. Results: Fifteen key clinical statements were proposed. The expert panel reached agreements on several important issues related to the management of prediabetes providing recommendations on the screening, diagnosis, lifestyle and pharmacological management of prediabetes. The expert panel also proposed changes in forthcoming clinical practice guidelines and suggested that the government should advocate early screening, detection, and intensive management of prediabetes. Conclusion: This document provides a comprehensive approach to the management of prediabetes in Malaysia in their daily activities and offer help in improving government policies and the decision-making process.