Diastolic dysfunction in patients with liver cirrhosis: A short-term, observational study at a Malaysian hospital

Author: Khairul Azlan Abdul Aziz, ¹ ; Nani Draman ² ; Wan Yus Haniff Wan Isa ³ ; Nazri Mustaffa ³
Author Information

1. Department of Medicine, Hospital Teluk Intan, Jalan Changkat Jong, Teluk Intan, Perak, Malaysia
2. Department of Family Medicine, School of Medical Sciences, Universiti Sains Malaysia, Jalan Raja Perempuan Zainab II, Kubang Kerian, Kelantan, Malaysia
3. Department of Medicine, School of Medical Sciences, Universiti Sains Malaysia, Jalan Raja Perempuan Zainab II, Kubang Kerian, Kelantan, Malaysia
Publication Type:Other Types
Keywords: Child-Pugh score, Cirrhotic cardiomyopathy; Liver cirrhosis; MELD score; Sodium restriction
From: The Medical Journal of Malaysia 2020;75(4):396-399
CountryMalaysia
Language:English
Abstract: Cirrhotic cardiomyopathy is a recognised complication of liver cirrhosis and predicts poor outcomes. Detection of diastolic dysfunction, an early indicator of left ventricular dysfunction can help identify those patients at risk of disease progression. In our study we showed that there was a high prevalence of diastolic dysfunction amongst patients with liver cirrhosis at our outpatient clinic, with the majority being Child-Pugh A/low MELD score. Multiple regression analysis indicated that age and sodium levels were significantly associated with the presence of diastolic dysfunction. This further reinforces the importance of dietary sodium restriction amongst patients with liver cirrhosis.