Risk factors and prevention strategies for chronic cough after robotic versus video-assisted thoracic surgery in non-small cell lung cancer patients
- VernacularTitle:达芬奇机器人与电视胸腔镜非小细胞肺癌术后慢性咳嗽危险因素分析及应对策略
- Author:
Ziheng WU
1
;
Wei XU
2
;
Shiguang XU
2
;
Bo LIU
2
;
Renquan DING
2
;
Xilong WANG
2
;
Xingchi LIU
2
;
Bo LI
2
;
Shumin WANG
2
Author Information
1. The Graduate Training Base of Jinzhou Medical University, General Hospital of Northern Theater Command, Shenyang, 110016, P.R.China
2. Department of Thoracic Surgery, General Hospital of Northern Theater Command, Shenyang, 110016, P.R.China
- Publication Type:Journal Article
- Keywords:
Da Vinci robot;
postoperative chronic cough;
non-small cell lung cancer;
enhanced recovery after surgery;
video-assisted thoracoscope
- From:
Chinese Journal of Clinical Thoracic and Cardiovascular Surgery
2020;27(11):1274-1280
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze risk factors for chronic cough after minimally invasive resection of non-small cell lung cancer (NSCLC) and explore the possible prevention measures. Methods A total of 128 NSCLC patients who received minimally invasive resection in 2018 in our hospital were enrolled, including 63 males and 65 females with an average age of 60.82±9.89 years. The patients were allocated into two groups: a robot-assisted thoracic surgery (RATS) group (56 patients) and a video-assisted thoracic surgery (VATS) group (72 patients). Chronic cough was assessed by visual analogue scale (VAS), meanwhile, other perioperative indicators were compared between the two groups. Univariate and multivariate logistic regression analyses were performed to identify risk factors for postoperative chronic cough and explore the prevention strategies. Results Overall, 61 (47.7%) patients were diagnosed with chronic cough after surgery, including 25 (44.6%) patients in the RATS group and 36 (50.0%) patients in the VATS group, and the difference was not statistically significant (P>0.05). Compared with the VATS group, the RATS group got shorter endotracheal intubation time (P=0.009) and less blood loss (P<0.001). The univariate analysis showed that age (P=0.014), range of surgery (P=0.021), number of dissected lymph nodes (P=0.015), preoperative cough (P=0.006), endotracheal intubation time (P=0.004) were the influencing factors for postoperative chronic cough. The multivariate analysis showed that age <57 years (OR=3.006, 95%CI 1.294-6.986, P=0.011), preoperative cough (OR=3.944, 95%CI 4.548-10.048, P=0.004), endotracheal intubation time ≥172 min (OR=2.316, 95%CI 1.027-5.219, P=0.043), lobectomy (OR=2.651, 95%CI 1.052-6.681, P=0.039) were the independent risk factors for chronic cough. Conclusion There is no statistical difference in postoperative chronic cough between the RATS and VATS groups. The RATS group gets less blood loss and shorter endotracheal intubation time. Patients with younger age (<57 years), preoperative cough, lobectomy, and longer duration of endotracheal intubation (≥172 min) are more likely to have chronic cough after surgery.
