Advances in pancreatic β-cell protective strategies
10.11665/j.issn.1000-5048.20200515
- VernacularTitle:胰岛β细胞保护策略研究进展
- Author:
Jing WANG
1
;
Hongxia LIU
;
Dongcheng CAI
;
Chaoyong HE
Author Information
1. 中国药科大学药学院药理系
- Publication Type:Journal Article
- Keywords:
ancreatic β cell;
insulin;
diabetes;
protective strategy;
advances
- From:
Journal of China Pharmaceutical University
2020;51(5):622-627
- CountryChina
- Language:Chinese
-
Abstract:
Pancreatic β cells, the only cells in the body that can synthesize and secrete insulin, can be damaged by a variety of pathological factors. Increasing attention has been paid to the studies of protecting pancreatic β cells in the treatment of diabetes. In this review, we highlight the studies that focus on enhancement of islet β cell function, reduction of islet β cell apoptosis, increase of islet β cell number and induction of islet β cell differentiation, providing novel targets and therapeutic strategies for the treatment of diabetes.
