Metastatic pattern of No.13 and No.14 intrapulmonary lymph nodes in patients with peripheral non-small cell lung cancer
- VernacularTitle:周围型非小细胞肺癌肺内第 13、14 组淋巴结转移规律研究
- Author:
Lei BI
1
,
2
;
Hong ZHANG
2
,
3
;
Zhongzhu LV
1
,
2
;
Yiping DENG
1
,
2
;
Tenghao RONG
1
,
2
;
Chaolun LIU
1
,
2
;
Mingjian GE
4
Author Information
1. Department of Cardiothoracic Surgery, The People&rsquo
2. s Hospital of Bishan District, Chongqing, 402760, P.R.China
3. Department of Traditional Chinese Medicine, The People&rsquo
4. Department of Cardiothoracic Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400000, P.R.China
- Publication Type:Journal Article
- Keywords:
Lung neoplasms;
intrapulmonary lymph node;
lymph node metastasis;
lymph node dissection
- From:
Chinese Journal of Clinical Thoracic and Cardiovascular Surgery
2020;27(10):1201-1206
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the clinical pattern of intrapulmonary lymph node metastasis and the significance of No.13 and No.14 lymph nodes biopsy in patients with non-small cell lung cancer (NSCLC). Methods The clinical data of 234 patients with primary peripheral NSCLC who underwent systemic dissection of intrathoracic lymph nodes and intrapulmonary lymph nodes in the First Affiliated Hospital of Chongqing Medical University between 2013 and 2015 were retrospectively analyzed. There were 159 males and 75 females, aged 36-89 (61.35±8.57) years. Statistical analysis was performed accordingly on hilar (No.10), interlobar (No.11), lobar (No.12) and segmental (No.13 and 14) sites of the samples of N1 lymph nodes after surgery. Results A total of 3 019 lymph nodes of No.10-14 were dissected in 234 patients (12.9 per patient). The 263 lymph nodes were positive with a rate of 8.71% (263/3 019) and lymph node metastasisa occured in 99 patients with a rate of 42.31% (99/234), among whom there were 40 patients of N1 metastasis, 48 of N1+N2 metastasis and 11 of N2 skipping metastasis. Routine pathological examination demonstrated No.13 and No.14 lymph nodes metastasis in 16 patients with a rate of 6.84% (16/234). In 886 dissected lymph nodes of No.13 and No.14, 86 lymph nodes showed metastasis with a rate of 9.71% (86/886). Of the patients with swelling hilar and mediastinal lymph nodes reported by preoperative CT scan, only 56.32% of them were confirmed with lymph node metastasis by postoperative histopathology; while 34.01% of the patients with normal size lymph nodes had lymph node metastasis. Conclusion In the surgical treatment of NSCLC, it is necessary to detect the metastasis of No. 13 and 14 lymph nodes and non-tumor parabronchial lymph nodes, which is helpful to obtain accurate postoperative TNM staging and is of great significance for guiding postoperative treatment. Preoperative CT is not a reliable method to judge lymph node metastasis, particularly for intrapulmonary lymph node metastasis.
