Changes of perioperative thyroid hormone in adult patients undergoing cardiac surgery under cardiopulmonary bypass
- VernacularTitle:体外循环下心脏外科手术成人患者围术期甲状腺激素水平变化分析
- Author:
Ling ZENG
1
;
Yuping XIANG
1
;
Tianhui LUO
1
;
Min LIN
1
;
Lu LIU
1
;
Yongjun QIAN
2
Author Information
1. Department of Thoracic Surgery ICU, West China Hospital, West China School of Nursing, Sichuan University, Chengdu, 610041, P.R.China
2. Department of Cardiovascular Surgery, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, 610041, P.R.China
- Publication Type:Journal Article
- Keywords:
Cardiac surgery;
cardiopulmonary bypass;
thyroid hormone;
perioperation
- From:
Chinese Journal of Clinical Thoracic and Cardiovascular Surgery
2020;27(09):1055-1058
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the changes of perioperative thyroid hormone in patients undergoing cardiac surgery under cardiopulmonary bypass, and to provide guidance for postoperative cardiac management. Methods The clinical data of 72 patients receiving cardiac surgery under cardiopulmonary bypass in our hospital from January to May 2019 were collected, including 35 males and 37 females, aged 19-72 (52.35±10.40) years. The changes of thyroid hormones before operation, 2 hours and 24 hours after operation were analyzed. Results There was a statistical difference in thyroid stimulating hormone (TSH), triiodothyronine (T3), tetraiodothyronine (T4) and free tetraiodothyronine (FT4) between postoperative 2 hours and preoperation (P<0.05). There was a statistical difference in TSH, T3, free triiodothyronine (FT3), T4 and FT4 between postoperative 24 hours and preoperation (P<0.05). There was a statistical difference in TSH, T3, FT3 and T4 between postoperative 24 hours and 2 hours (P<0.05). Postoperatively T3 and FT3
decreased, TSH increased and then decreased while T4 and FT4 were within the normal range. Repeated measures analysis of variance showed a statistical difference of time effect in TSH, T3, FT3, T4 and FT4. Conclusion Patients with cardiac surgery under cardiopulmonary bypass have different thyroid hormones postoperatively compared with preoperatively. T3 and FT3 decrease, TSH increases and then decreases, while T4 and FT4 are in the normal range. The results require further large-scale, multi-center, high-quality clinical studies to be confirmed.
