Regulatory effect of tumor-associated neutrophils in the development and progression of liver cancer
DOI:10.3969/j.issn.1001-5256.2020.09.043
- VernacularTitle:肿瘤相关中性粒细胞在肝癌发生发展中的调控作用
- Author:
Lei HU
1
;
Li2 GAO
;
Hermann3 DIRK
;
Aidong2,3 CHEN
Author Information
1. Guiyang Maternal and Child Health Hospital, Guiyang 550003, China
- Publication Type:Research Article
- Keywords:
liver neoplasms;
tumor-associated neutrophils;
tumor microenvironment
- From:
Journal of Clinical Hepatology
2020;36(9):2100-2102
- CountryChina
- Language:Chinese
-
Abstract:
The incidence rate of liver cancer keeps increasing in recent years, and this disease has difficulties in early diagnosis, poor treatment outcome, and poor prognosis. This article describes the research advances in tumor-associated neutrophils involved in the regulation of liver tumor microenvironment and points out that they can be used as a new target for the treatment of liver cancer. Combined with tumor-associated macrophages, regulatory T cells, and various cytokines in liver tumor microenvironment, tumor-associated neutrophils can achieve a systemic anti-tumor effect and thus bring hopes to the treatment of liver cancer.
