Churg-Strauss Syndrome Showing Green Colored Polycyclic Patches.
- Author:
Moon Seub SHIN
1
;
Soo Jin KIM
;
Seong Hyun KIM
;
Hai Jin PARK
Author Information
1. Department of Dermatology, Ilsan Paik Hospital, College of Medicine, Inje University, Goyang, Korea. stratum@hanmail.net
- Publication Type:Case Report
- Keywords:
Churg-Strauss syndrome;
Eosinophilia;
Vasculitis
- MeSH:
Adult;
Asthma;
Biopsy;
Buttocks;
Churg-Strauss Syndrome;
Collagen;
Dermis;
Dust;
Endothelial Cells;
Eosinophilia;
Eosinophils;
Extremities;
Female;
Finger Joint;
Hand;
Humans;
Lower Extremity;
Methylprednisolone;
Rhinitis;
Rhinitis, Allergic, Perennial;
Sensation;
Skin;
Systemic Vasculitis;
Vasculitis
- From:Korean Journal of Dermatology
2011;49(9):812-817
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Churg-Strauss syndrome (CSS) or allergic granulomatous angiitis is a rare systemic vasculitis with tissue and blood eosinophilia. A 37-year-old woman with a 2-year history of allergic rhinitis and asthma presented with polycyclic patches on both extremities and trunk. Laboratory studies revealed peripheral blood eosinophilia, hyper-IgE, and positivity for ANA (1:40, speckled pattern). Skin biopsy specimens showed endothelial cell swelling, perivascular and interstitial eosinophilic infiltration with nuclear dust in the dermis. She was treated with methylprednisolone and showed an improvement in symptoms. Two years later she developed a tingling sensation on her right hand and right lower extremity along with aggravation of skin lesions. The skin examination revealed erythematous papules and greenish patches on buttock and finger joints. On the histological examination of the patches on the buttock, prominent extravascular eosinophilic infiltration, endothelial cell swelling and degenerative collagen fibers were observed in the dermis.
