Value of noninvasive indicators in predicting clinical outcome events of liver cirrhosis
DOI:10.3969/j.issn.1001-5256.2020.09.006
- VernacularTitle:无创性指标对肝硬化临床终点事件的预测
- Author:
Mingyi XU
1
;
Zixin XU
Author Information
1. Department of Gastroenterology, The First People’s Hospital Affiliated to Shanghai Jiao Tong University, Shanghai 200080, China
- Publication Type:Research Article
- Keywords:
liver cirrhosis;
biomarkers;
elasticity imaging techniques
- From:
Journal of Clinical Hepatology
2020;36(9):1941-1946
- CountryChina
- Language:Chinese
-
Abstract:
At present, more and more studies have been conducted on noninvasive diagnostic indicators for liver cirrhosis, but no consensus has been reached on the association of noninvasive diagnostic indicators with clinical outcome events and their predictive value. This article summarizes the value of noninvasive indicators, including serological markers, serum diagnostic models, and liver stiffness measurement (LSM), in predicting the clinical outcome events of liver cirrhosis. The noninvasive diagnostic method of serological markers (such as platelet count and FibroTest) combined with LSM can assess the stage of liver fibrosis and predict the outcome events and long-term prognosis of liver cirrhosis, and thus it has been included in Chinese and global guidelines and has been widely used in clinical practice. The use of new combinations (such as LSM combined with serological markers or diagnostic models) or a step-by-step calculation method shows the hope of modification to realize individualized dynamic clinical management of patients, reduce or avoid the occurrence of clinical outcome events of liver cirrhosis, and bring maximum benefit to patients with liver cirrhosis.
