Clinical features of coronavirus disease 2019 in children aged <18 years in Jiangxi, China: an analysis of 23 cases.
- Author:
Hua-Ping WU
1
;
Bing-Fei LI
;
Xiao CHEN
;
Hua-Zhu HU
;
Shu-Ai JIANG
;
Hao CHENG
;
Xin-He HU
;
Jian-Xin TANG
;
Fu-Chu ZHONG
;
Ling-Wen ZENG
;
Wei YU
;
Yan YUAN
;
Xian-Fei WU
;
Yu-Ping LI
;
Zong-Li ZHENG
;
Tian-Bo PAN
;
Zhi-Xing WU
;
Jin-Feng YUAN
;
Qiang CHEN
Author Information
1. Department of Pediatrics, Jiangxi Provincial Children's Hospital/Children's Hospital, Nanchang University, Nanchang 330006, China. jx-cq@163.com.
- Publication Type:Journal Article
- MeSH:
Adolescent;
Betacoronavirus;
Child;
Child, Preschool;
China;
Coronavirus Infections;
Humans;
Infant;
Pandemics;
Pneumonia, Viral;
Retrospective Studies
- From:
Chinese Journal of Contemporary Pediatrics
2020;22(5):419-424
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To study the clinical features of coronavirus disease 2019 (COVID-19) in children aged <18 years.
METHODS:A retrospective analysis was performed from the medical data of 23 children, aged from 3 months to 17 years and 8 months, who were diagnosed with COVID-19 in Jiangxi, China from January 21 to February 29, 2020.
RESULTS:Of the 23 children with COVID-19, 17 had family aggregation. Three children (13%) had asymptomatic infection, 6 (26%) had mild type, and 14 (61%) had common type. Among these 23 children, 16 (70%) had fever, 11 (48%) had cough, 8 (35%) had fever and cough, and 8 (35%) had wet rales in the lungs. The period from disease onset or the first nucleic acid-positive detection of SARS-CoV-2 to the virus nucleic acid negative conversion was 6-24 days (median 12 days). Of the 23 children, 3 had a reduction in total leukocyte count, 2 had a reduction in lymphocytes, 2 had an increase in C-reactive protein, and 2 had an increase in D-dimer. Abnormal pulmonary CT findings were observed in 12 children, among whom 9 had patchy ground-glass opacities in both lungs. All 23 children received antiviral therapy and were recovered.
CONCLUSIONS:COVID-19 in children aged <18 years often occurs with family aggregation, with no specific clinical manifestation and laboratory examination results. Most of these children have mild symptoms and a good prognosis. Epidemiological history is of particular importance in the diagnosis of COVID-19 in children aged <18 years.
