Pregnant women complicated with COVID-19: a clinical analysis of 3 cases.
10.3785/j.issn.1008-9292.2020.03.08
- Author:
Xu CHEN
1
;
Yang LI
1
;
Jinxi WANG
1
;
Hongliu CAI
2
;
Hongcui CAO
3
;
Jifang SHENG
3
Author Information
1. Department of Obstetrics and Gynecology, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China.
2. Department of Critical Care Medicine, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China.
3. Department of Infectious Diseases, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China.
- Publication Type:Case Reports
- MeSH:
Antiviral Agents;
therapeutic use;
Betacoronavirus;
isolation & purification;
Cesarean Section;
Coronavirus Infections;
complications;
drug therapy;
Female;
Glucocorticoids;
therapeutic use;
Humans;
Oxygen;
therapeutic use;
Pandemics;
Pneumonia, Viral;
complications;
drug therapy;
Pregnancy;
Pregnancy Complications, Infectious;
drug therapy;
pathology;
Pregnancy Outcome;
Retrospective Studies;
Treatment Outcome;
gamma-Globulins;
therapeutic use
- From:
Journal of Zhejiang University. Medical sciences
2020;49(2):240-244
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To analyze the clinical characteristics and pregnancy outcomes of pregnant women complicated with coronavirus disease 2019 (COVID-19).
METHODS:The clinical data of 3 pregnant women with COVID-19 admitted to the First Affiliated Hospital of Zhejiang University School of Medicine from January 19 to February 10, 2020 were retrospectively analyzed.
RESULTS:There was one case in the first-trimester pregnancy (case 1), one in the second-trimester pregnancy (case 2) and one in third-trimester pregnancy (case 3). Cough, fever, fatigue, lung imaging changes were the main manifestations. The white cell count, lymphocyte percentage had no significantly changes in case 1 and case 3, while the levels of C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), IL-6 and IL-10 elevated. The lymphocyte count and lymphocyte percentage decreased and the inflammatory indicators significantly increased in case 2. All patients were treated with antiviral, antitussive, oxygen inhalation; case 3 received glucocorticoids, case 2 with severe illness received glucocorticoids and additionally gamma globulin. All three cases were cured and discharged. Case 1 with early pregnancy chose to terminate pregnancy after discharge; case 2 chose to continue pregnancy without obstetric complications; and case 3 had cesarean section delivery due to abnormal fetal heart monitoring.
CONCLUSIONS:The report shows that COVID-19 in pregnancy women could be cured with active treatment, and the maternal and fetal outcomes can be satisfactory.
