A rapid identification of authenticity and specifications of Chinese medicine Fritillariae Cirrhosae Bulbus based on E-eye technology.
10.19540/j.cnki.cjcmm.20200601.301
- Author:
Rui-Xin LIU
1
;
Xiao-Jia HAO
2
;
Hui-Jie ZHANG
2
;
Lu ZHANG
3
;
Xin-Jing GUI
3
;
Zhao-Zhou LIN
4
;
Chong-Nian LUO
4
;
Liang-Yu TIAN
2
;
Yan-Li WANG
2
;
Wen-Hao FENG
2
;
Jing YAO
3
;
Xue-Lin LI
1
Author Information
1. Henan University of Chinese Medicine Zhengzhou 450008, China Department of Pharmacy, the First Affiliated Hospital of Henan University of Chinese Medicine Zhengzhou 450000, China Research Center for Modern Engineering for Clinical Application of Chinese Medicine Decoction Pieces in Henan Province Zhengzhou 450000, China Co-construction Collaborative Innovation Center for Chinese Medicine and Respiratory Diseases Co-constructed by Province & Ministry, Henan University of Chinese Medicine Zhengzhou 450000, China.
2. Henan University of Chinese Medicine Zhengzhou 450008, China.
3. Department of Pharmacy, the First Affiliated Hospital of Henan University of Chinese Medicine Zhengzhou 450000, China Research Center for Modern Engineering for Clinical Application of Chinese Medicine Decoction Pieces in Henan Province Zhengzhou 450000, China Co-construction Collaborative Innovation Center for Chinese Medicine and Respiratory Diseases Co-constructed by Province & Ministry, Henan University of Chinese Medicine Zhengzhou 450000, China.
4. Beijing Hospital of Traditional Chinese Medicine, Capital Medical University Beijing 100010, China Beijing Institute of Traditional Chinese Medicine Beijing 100035, China.
- Publication Type:Journal Article
- Keywords:
Fritillariae Cirrhosae Bulbus;
commodity specification;
electronic-eye;
genuine/false;
identification model;
quality identification
- MeSH:
Drugs, Chinese Herbal;
Fritillaria;
Medicine, Chinese Traditional;
Plant Roots;
Technology
- From:
China Journal of Chinese Materia Medica
2020;45(14):3441-3451
- CountryChina
- Language:Chinese
-
Abstract:
The quality of traditional Chinese medicine tablets is correlated with clinical efficacy and drug safety, and plays a great role in promoting the development of traditional Chinese medicine. However, the existing traditional artificial identification and modern instrument detection in terms of accuracy and timeliness have both advantages and disadvantages. Therefore, how to quickly and accurately identify the quality of traditional Chinese medicine tablets has become a high-profile issue. The purpose of this paper is to explore the feasibility of the application of electronic eye technology in the study of rapid identification of traditional Chinese medicine quality. A total of 80 batches of samples were collected and tested by Fritillariae Cirrhosae Bulbus for traditional empirical identification(M_1) and modern pharmacopeia(M_2). The optical data was collected from electronic eyes, and the chemical metrology was used to establish suitable discrimination models(M_3). Four authenticity and commodity specification models, namely identification analysis(DA), minimum bidirectional support vector machine(LS-SVM), partial minimum two-multiplier analysis(PLS-DA), main component analysis identification analysis(PCA-DA), were established, respectively. The accuracies of the authenticity identification models were 82.5%, 90.0%, 96.2% and 93.8%, while the accuracies of the commodity specification identification models were 89.3%, 96.0%, 90.7% and 97.3%, respectively. The models were well judged, the authenticity identification was based on the final identification model of PLS-DA, and the commodity specification was based on the final identification model of PCA-DA. There was no significant difference between its accuracy and M_1, and the time of determination was much shorter than M_2(P<0.01). Therefore, electronic-eye technology could be used for the rapid identification of the quality of Fritillariae Cirrhosae Bulbus.
