A new macrocyclic phenolic glycoside from Sorghum vulgare root.
10.19540/j.cnki.cjcmm.20200408.202
- Author:
Shan-Li WANG
1
;
Lang ZHOU
2
;
An-Xiang ZHU
2
;
Xiao-Sheng YANG
2
;
Qi-Ji LI
2
;
Juan YANG
2
Author Information
1. Pharmaceutical College, Guizhou University Guiyang 550002, China State Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Medical University Guiyang 550014, China the Key Laboratory of Chemistry for Natural Products of Guizhou Province and Chinese Academy of Sciences Guiyang 550014, China.
2. State Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Medical University Guiyang 550014, China the Key Laboratory of Chemistry for Natural Products of Guizhou Province and Chinese Academy of Sciences Guiyang 550014, China.
- Publication Type:Journal Article
- Keywords:
Sorghum vulgare root;
chemical constituents;
dimeric double lactonol
- MeSH:
Cardiac Glycosides;
Glucosides;
Glycosides;
Phenols;
Sorghum
- From:
China Journal of Chinese Materia Medica
2020;45(15):3689-3693
- CountryChina
- Language:Chinese
-
Abstract:
Eleven compounds were isolated and purified from Sorghum vulgare root extract, through column chromatography over silica gel, MCI gel, and preparative HPLC. Their structures were established by MS, 1 D NMR and 2 D NMR data as sorgholide A(1), β-sitosterol(2), stigmastero(3), daucosterol(4), 4-methoxycinnamic acid(5), taxiphyllin(6), chlorogenic acid(7), p-hydroxybenzaldehyde(8), succini acid(9), trans-p-hydroxycinnamic acid(10), obtusalin(11). Compounds 4,5 and 9-11 were reported from this species for the first time, and compound 1 is the first 24 ring dimeric double lactonol glycoside formed by reverse polymerization of p-hydroxyphenylacetate glucoside, named sorgholide A.
