Research progress in combination applications of antidepressant drugs.
10.19540/j.cnki.cjcmm.20200509.601
- Author:
Huan-le LIU
1
;
Fu-Xiao WEI
1
;
Xue-Mei QIN
1
;
Xiao-Jie LIU
1
Author Information
1. Modern Research Center for Traditional Chinese Medicine, Shanxi University Taiyuan 030006, China Shanxi Key Laboratory of Active Constituents Research and Utilization of Tradition Chinese Medicine Taiyuan 030006, China.
- Publication Type:Journal Article
- Keywords:
antidepressant drugs;
depression;
drug combinations;
secondary depression;
treatment resistant depression
- MeSH:
Antidepressive Agents;
Drug Interactions;
Humans;
Medicine, Chinese Traditional
- From:
China Journal of Chinese Materia Medica
2020;45(16):3776-3783
- CountryChina
- Language:Chinese
-
Abstract:
Depression is a common affective disorder. The application of antidepressants can significantly alleviate the symptoms of depression, which is the most important way to treat depression in clinical practice. Due to the complex etiology, wide variety, as well as diversity and severity of serious concomitant symptoms, rational addition of other drugs into antidepressants can significantly improve the cure rates of depression, reduce adverse reactions, and improve patient compliances. Therefore, the combined applications of differential drugs have been commonly used in clinic. In this paper, more than 600 literatures about depression from 2010 to 2019 were collected based on the key words of antidepressant, depression, combined medication, synergism and increase efficiency. Based on this, by summarizing and classifying the existing combinations of antidepressant drugs, this paper systematically expounds the current combined applications of antidepressant drugs in three categories, i.e. western medicines combined with western medicines, western medicines combined with traditional Chinese medicines, and traditional Chinese medicines combined with traditional Chinese medicines, in the expectation of providing the direction and basis for the selection of rational combinations of antidepressant drugs in clinic.
