Advance in functional bladder engineering.
10.7507/1001-5515.201911075
- Author:
Xiuzhen ZHANG
1
;
Qiuzhu CHEN
1
;
Yiqi ZHANG
1
;
Huiqi XIE
1
Author Information
1. The Laboratory of Stem Cell and Tissue Engineering, West China Hospital, Sichuan University, Chengdu 610041, P.R.China.
- Publication Type:Journal Article
- Keywords:
bladder tissue engineering;
growth factor;
scaffold;
seeding cell
- MeSH:
Humans;
Intercellular Signaling Peptides and Proteins;
Regenerative Medicine;
trends;
Tissue Engineering;
trends;
Tissue Scaffolds;
Urinary Bladder
- From:
Journal of Biomedical Engineering
2020;37(2):200-206
- CountryChina
- Language:Chinese
-
Abstract:
Bladder has many important functions as a urine storage and voiding organ. Bladder injury caused by various pathological factors may need bladder reconstruction. Currently the standard procedure for bladder reconstruction is gastrointestinal replacement. However, due to the significant difference in their structure and function, intestinal segment replacement may lead to complications such as hematuria, dysuria, calculi and tumor. With the recent advance in tissue engineering and regenerative medicine, new techniques have emerged for the repair of bladder defects. This paper reviews the recent progress in three aspects of urinary bladder tissue engineering, i.e., seeding cells, scaffolds and growth factors.
