The application of fluorine-18-fluorodeoxyglucose positron emission tomography/computed tomography in inflammation and infectious disease.
10.7507/1001-5515.202002030
- Author:
Yutang YAO
1
,
2
;
Xiaohong OU
3
Author Information
1. Department of Nuclear Medicine, West China Hospital, Sichuan University, Chengdu 610041, P.R.China
2. PETCT center, Department of Nuclear Medicine,, Sichuan Cancer Hospital&Institute, Sichuan Cancer Center, School of Medicine, University of Electronic Science and Technology of China, Chengdu 610041, P.R.China.
3. Department of Nuclear Medicine, West China Hospital, Sichuan University, Chengdu 610041, P.R.China.
- Publication Type:Journal Article
- Keywords:
2-［18F］-fluoro-2-deoxy-D-glucose;
infection;
inflammation;
positron emission tomography/computed tomography
- MeSH:
Fluorodeoxyglucose F18;
Humans;
Inflammation;
Positron Emission Tomography Computed Tomography;
Radiopharmaceuticals
- From:
Journal of Biomedical Engineering
2020;37(4):730-735
- CountryChina
- Language:Chinese
-
Abstract:
2-［ F］-fluoro-2-deoxy-D-glucose positron emission tomography/computed tomography ( F-FDG PET/CT) combining positron emission tomography with computed tomography is used to evaluate the body's glucose metabolic changes under different conditions. In addition to its established role in oncological imaging, F-FDG PET/CT has clinical utility in suspected inflammation and infection. The technique can identify the source of infection in a timely fashion ahead of morphological changes, map the extent and severity of inflammation, guide the site for tissue biopsy and assess therapy response. This article reviewed the use of F-FDG PET/CT in infection and inflammation, such as fever of unknown origin, sarcoidosis, vessel vasculitis, osteomyelitis, joint prosthesis or implant-related complications, human immunodeficiency virus-related infections, and other indications, such as inflammatory bowel disease, so as to provide reference for clinicians to select F-FDG PET/CT to help them in the diagnosis and treatment of inflammatory diseases.
