Studies on chemical constituents of stems of Herpetospermum pedunculosum.
10.19540/j.cnki.cjcmm.20200227.201
- Author:
Zhi-Ying FENG
1
;
Ying-Xiong MA
1
;
Hong WANG
1
;
Min CHEN
1
Author Information
1. College of Pharmaceutical Sciences, Southwest University Chongqing 400715, China.
- Publication Type:Journal Article
- Keywords:
Herpetospermum pedunculosum;
chemical constituents;
stems
- MeSH:
Chromatography, High Pressure Liquid;
Cucurbitaceae
- From:
China Journal of Chinese Materia Medica
2020;45(11):2571-2577
- CountryChina
- Language:Chinese
-
Abstract:
This project is to study chemical compositions from the stems of Herpetospermum pedunculosum. Twenty-two compounds were isolated from the 70% acetone extract of the stems of H. pedunculosum by column chromatography on Sephadex LH-20, semi-preparative HPLC and preparative TLC. Their structures were elucidated by their physicochemical properties and spectroscopic data as N-benzyltyramine(1), α-spinasterol(2),(2S)-1-O-heptatriacontanoyl glycerol(3), 5,7-dihydroxychromanone(4), methyl 2β,3β-dihydroxy-D:C-friedoolean-8-en-29-oate(5), p-hydroxy benzyl alcohol(6), p-hydroxybenzoate(7), p-hydroxy cinnamic acid(8), 1H-indol-3-carboxylic acid(9), rhodiocyanoside B(10), rhodiolgin(11), rhodiosin(12), 9,12,13-trihydroxy-10(E)-octadecenoic acid(13), cylo-(Tyr-Leu)(14), matteflavoside A(15), loliolide(16), 1H-indol-3-carboxaldehyde(17),(+)-dehydrovomifoliol(18), 3-hydroxy-5α,6α-epoxy-β-ionone(19), 3-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-2-[4-(3-hydroxy-1-propen-1-yl)-2-methoxyphenoxy]-1-propanone(20), 7-en-nonadecanoic acid monoglyceride(21), vanillic acid(22). Compound 1 is a new natural product, while compounds 3-15 were isolated from this plant for the first time.
