Two new phenylpropanoid amide glycosides from whole plants of Corydalis racemosa.
10.19540/j.cnki.cjcmm.20200220.202
- Author:
Hui-Na YAO
1
;
Hang ZHANG
1
;
Wen-Xuan WANG
1
;
Ni-Li ZAN
1
;
Di-Fa LIU
2
;
Yun-Fang ZHAO
1
;
Jiao ZHENG
1
;
Peng-Fei TU
1
;
Jun LI
3
Author Information
1. Modern Research Center for Traditional Chinese Medicine, School of Chinese Materia Medica, Beijing University of Chinese Medicine Beijing 100029, China.
2. State Key Laboratory of Innovative Natural Medicine and Traditional Chinese Medicine Injections, Jiangxi Qingfeng Pharmaceutical Co., Ltd. Ganzhou 341000, China.
3. Modern Research Center for Traditional Chinese Medicine, School of Chinese Materia Medica, Beijing University of Chinese Medicine Beijing 100029, China Beijing Key Lab for Quality Evaluation of Chinese Materia Medica, Beijing University of Chinese Medicine Beijing 102488, China.
- Publication Type:Journal Article
- Keywords:
Corydalis racemosa;
chemical constituents;
phenylpropanoid amide
- MeSH:
Amides;
Chromatography, High Pressure Liquid;
Corydalis;
Glucosides;
Glycosides
- From:
China Journal of Chinese Materia Medica
2020;45(10):2411-2416
- CountryChina
- Language:Chinese
-
Abstract:
Two new phenylpropanoid amide glycosides and ten analogues were isolated from the CH_2Cl_2 layer of 95% ethanol extract of the whole plants of Corydalis racemosa by using various chromatographic techniques, including silica gel, Sephadex LH-20, ODS column chromatographies, and semi-preparative HPLC. Their structures were identified on the basis of physicochemical properties, MS, NMR, and IR spectroscopic data as N-cis-sinapoyltyramine-4'-O-β-glucoside(1), N-cis-sinapoyl-3-methoxytyramine-4'-O-β-glucoside(2), N-cis-sinapoyltyramine(3), N-cis-feruloyltyramine(4), N-trans-cinnamoyltyramine(5), N-trans-feruloylphenethylamine(6), N-trans-p-methoxycinnamoyl-3-hydoxyoctopamine(7), N-cis-feruloyl-3-methoxytyramine(8), N-trans-feruloyltyramine(9), N-trans-feruloyl-3-methoxytyramine(10), N-trans-sinapoyltyramine(11), and N-trans-p-coumaroyltyramine(12). Compounds 1 and 2 are new compounds. Compounds 3-7 are obtained from the plants of Papaveraceae for the first time, and compounds 8-12 are firstly isolated from C. racemosa.
